Salbutamol Impurity 58 CAS CATO-C4X-1176158
| CAS No. | CATO-C4X-1176158 |
| Molecular Formula | C27H31NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Salbutamol Impurity 58 (CAS CATO-C4X-1176158, C27H31NO3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Salbutamol Impurity 58 (C27H31NO3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Salbutamol Impurity 58 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H31NO3 HCl |
| Molecular Weight | 454.01 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Salbutamol Standards
- Salbutamol Impurity 130 (CAS 115061-55-7)
- Salbutamol Impurity 134 (CAS 115787-50-3)
- Salbutamol Impurity 55 (CAS 115787-52-5)
- Salbutamol Impurity 85 (CAS 115787-52-5（free base）)
- Salbutamol Impurity 87 (CAS 115787-53-6)
- Salbutamol-d3 (CAS 1219798-60-3)
- Salbutamol Impurity 75 (CAS 1221726-71-1)
- Salbutamol Impurity 146 (CAS 124658-76-0)
Recommended Standards
- Esmolol Impurity 57 (CAS CATO-C4X-189157)
- Upadacitinib Impurity 173 (CAS CATO-C4X-2405173)
- Bilastine Impurity 78 (CAS 1638785-22-4)
- 2-amino-4-chloro-5-methylbenzenesulfonyl chloride (CAS 104613-64-1)
- Dalilesen impurity 27 (CAS CATO-C4X-301027)
- N-(2-methoxybenzyl)-4-(p-tolyl)thiazol-2-amine (CAS 554438-84-5)
- (3,5-Bis(trifluoromethyl)phenyl)methanol (CAS 32707-89-4)
- 3-[(4-Fluorophenyl)thio]-2-hydroxy-2-methylpropanoic acid (CAS 339530-91-5)
- (3R,7AS)-7a-methyl-3-phenyl-2,3-dihydropyrrolo[2,1-b]oxazol-5(7ah)-one (CAS 211240-56-1)
- Anorexigenic Peptide (CAS 69275-10-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com