Salbutamol Impurity 216 CAS CATO-C4X-1176216
| CAS No. | CATO-C4X-1176216 |
| Molecular Formula | C26H40N2O5 |
| Molecular Weight | 460.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Salbutamol Impurity 216 (CAS CATO-C4X-1176216), a pharmacopoeial impurity reference standard (molecular formula C26H40N2O5, MW 460.61 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Salbutamol Impurity 216 (C26H40N2O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Salbutamol Impurity 216 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H40N2O5 |
| Molecular Weight | 460.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥98% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Salbutamol Standards
- Salbutamol EP Impurity F (CAS 147663-30-7)
- Salbutamol Impurity 176 (CAS CATO-C4X-1176176)
- Salbutamol EP Impurity N (R-Isomer) (CAS CATO-C4X-1176200)
- Salbutamol Impurity 214 (CAS CATO-C4X-1176214)
- Salbutamol Impurity 215 (CAS CATO-C4X-1176215)
- Salbutamol EP impurity N (CAS 149222-15-1)
- Salbutamol Impurity 82 (CAS CATO-C4X-117682)
- Salbutamol Impurity 175 (CAS CATO-C4X-1176175)
Recommended Standards
- Bisoprolol EP Impurity D (CAS 1225195-71-0)
- Ritonavir Impurity 60 (CAS 2454100-44-6)
- Gadobutrol Impurity 16 (CAS CATO-C4X-212016)
- Gadoteridol Impurity 19 (CAS CATO-C4X-225719)
- Tiotropium impurity 48 (CAS CATO-C4X-176448)
- Nefopam Impurity 6 (CAS 69984-25-4)
- Mianserin EP Impurity A (CAS 57321-32-1)
- 7-(Hydroxymethyl)indazole (CAS 1092961-09-5)
- Linagliptin Impurity 72 (CAS CATO-C4X-110172)
- 5-(3-Chloro-4-methoxyphenyl)-4-methylisoxazole (CAS 1399655-05-0)
- 2-((2-Acetamidocyclohexyl)(cyclopropyl)amino)acetic acid (CAS 1353969-47-7)
- 6-(M-tolyloxy)pyridin-3-amine (CAS 928003-17-2)
- (5-(4-Bromopyridin-2-yl)furan-2-yl)boronic acid (CAS 2225176-10-1)
- Biotinyl-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802086-28-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com