Teriflunomide Impurity 5 CAS 220512-86-7
| CAS No. | 220512-86-7 |
| Molecular Formula | C12H9F3N2O2 |
| Molecular Weight | 270.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Teriflunomide Impurity 5 (C12H9F3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 270.21 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Teriflunomide Impurity 5 (CAS 220512-86-7), a pharmacopoeial impurity reference standard (molecular formula C12H9F3N2O2, MW 270.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Teriflunomide Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N2O2 |
| Molecular Weight | 270.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Teriflunomide Standards
- (E)-Teriflunomide (CAS 214782-56-6)
- Teriflunomide Impurity 6 (CAS 62004-05-1)
- Teriflunomide Impurity C53 (CAS 1011244-72-6)
- Teriflunomide impurity 2 (CAS CATO-C4X-31202)
- Teriflunomide impurity 1 (CAS CATO-C4X-31201)
- Teriflunomide Impurity 2 (CAS 69066-42-8)
- Teriflunomide Impurity 7 (CAS 854677-43-3)
- Teriflunomide Impurity 4 (CAS CATO-C4X-31204)
Recommended Standards
- Leflunomide EP Impurity B (Teriflunomide) (CAS 163451-81-8)
- Leflunomide EP Impurity F (CAS 1403564-06-6)
- Clenproperol-d7 (CAS 1173021-09-4)
- Leflunomide EP Impurity E (CAS 208401-20-1)
- Lurasidone Impurity 51 (CAS 1318074-22-4)
- Dapoxetine Impurity 1 (CAS 119357-22-1)
- Saxagliptin Impurity 73 (CAS CATO-C4X-104973)
- N-(4-Aminophenyl)-2-(2-methylphenoxy)propanamide (CAS 954271-80-8)
- 3-Chloro-N-ethyl-4,5-dimethoxybenzamide (CAS 878471-54-6)
- (2-(1,1-Difluoroethyl)phenyl)methanol (CAS 1783383-15-2)
- tert-Butyl 3-(hydroxymethyl)-5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate (CAS 1251020-23-1)
- 1-(3-Isopropyl-1-methyl-5-vinyl-1H-pyrazol-4-yl)-3-methylbutan-1-one (CAS 1956365-46-0)
- 5-(2-Fluorophenyl)-1,2-dihydro-3h-1,2,4-triazol-3-imine (CAS 313662-92-9)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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