Chlorphenamine impurity 48 CAS CATO-C4X-118848
| CAS No. | CATO-C4X-118848 |
| Molecular Formula | C14H12ClN |
| Molecular Weight | 229.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Chlorphenamine impurity 48 (C14H12ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Chlorphenamine impurity 48 (CAS CATO-C4X-118848, C14H12ClN) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Chlorphenamine impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12ClN |
| Molecular Weight | 229.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorphenamine Standards
- Chlorphenamine Impurity 30 (CAS CATO-C4X-118830)
- Chlorphenamine impurity 49 (CAS CATO-C4X-118849)
- Chlorphenamine Impurity 21 (CAS 5005-37-8)
- Chlorphenamine Impurity 25 (CAS 122376-68-5)
- Chlorphenamine impurity 58 (CAS 123517-65-7)
- Chlorphenamine Impurity 60 (CAS 1081516-68-8)
- Chlorphenamine Impurity 59 (CAS CATO-C4X-118859)
- Chlorphenamine impurity 56 (CAS CATO-C4X-118856)
Recommended Standards
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- Ethyl 2-(m-tolyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylate (CAS 2416673-84-0)
- (1S,3R)-3-fluorocyclopentane-1-carboxylic acid (CAS 2306246-42-2)
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