Apixaban Impurity 155 CAS 1928718-22-2
| CAS No. | 1928718-22-2 |
| Molecular Formula | C26H27N5O4 |
| Molecular Weight | 473.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Apixaban Impurity 155 (CAS 1928718-22-2, C26H27N5O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Apixaban Impurity 155 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 473.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Apixaban Impurity 155 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H27N5O4 |
| Molecular Weight | 473.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 5 |
Related Apixaban Standards
- Apixaban Impurity 137 (CAS CATO-C4X-1088137)
- Apixaban Impurity 164 (CAS CATO-C4X-1088164)
- Apixaban Impurity 3 (BMS-778960-01) (CAS 2098457-92-0)
- Apixaban Impurity 4 (BMS-728626-01) (CAS 1686149-74-5)
- Apixaban Impurity 8 (CAS 1074549-87-3)
- Apixaban Impurity 87 (CAS CATO-C4X-108887)
- Apixaban Impurity 88 (CAS CATO-C4X-108888)
- Apixaban Impurity 6 (CAS 1074365-84-6)
Recommended Standards
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- 3-(4-Bromobenzyl)quinazolin-4(3H)-one (CAS 302913-19-5)
- 1365963-44-5 3-[(2,3-Dimethyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]benzoic acid MFCD22056539 (CAS 1365963-44-5)
- 2H-Imidazo[4,5-b]quinoxaline (CAS 13090-17-0)
- N-(5-Chloro-2-fluorophenyl)hydrazinecarbothioamide (CAS 1155049-13-0)
- DBCO-NH-Boc (CAS 1539290-74-8)
- 2-((6-(Thiophen-2-yl)pyridazin-3-yl)oxy)ethan-1-amine (CAS 1283109-49-8)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com