Lapatinib Impurity 44 CAS CATO-C4X-119144
| CAS No. | CATO-C4X-119144 |
| Molecular Formula | C29H25ClFN5O5S |
| Molecular Weight | 610.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lapatinib Impurity 44 (CAS CATO-C4X-119144), a pharmacopoeial impurity reference standard (molecular formula C29H25ClFN5O5S, MW 610.06 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C29H25ClFN5O5S, Lapatinib Impurity 44 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 610.06 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lapatinib Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H25ClFN5O5S |
| Molecular Weight | 610.06 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Lapatinib Standards
- Lapatinib Impurity 42 (CAS CATO-C4X-119142)
- Lapatinib Impurity 46 (CAS 320337-10-8)
- Lapatinib impurity 36 (CAS CATO-C4X-119136)
- Lapatinib Impurity 22 (CAS 1360431-86-2)
- Lapatinib-d4 (CAS 1184264-15-0)
- Lapatinib Impurity 43 (CAS CATO-C4X-119143)
- Lapatinib 2-Fluoro Impurity (CAS 1393112-45-2)
- Lapatinib (CAS 231277-92-2)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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