Eltrombopag Impurity 136 CAS CATO-C4X-1198136
| CAS No. | CATO-C4X-1198136 |
| Molecular Formula | C20H17NO3 |
| Molecular Weight | 319.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Eltrombopag Impurity 136 (CAS CATO-C4X-1198136) is a certified pharmaceutical impurity reference standard with the molecular formula C20H17NO3 and a molecular weight of 319.35 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Eltrombopag Impurity 136 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 319.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Eltrombopag Impurity 136 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H17NO3 |
| Molecular Weight | 319.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 14 (CAS CATO-C4X-119814)
- Eltrombopag Impurity 15 (CAS CATO-C4X-119815)
- Eltrombopag Impurity 82 (CAS 725241-64-5)
- Eltrombopag Impurity 91 (CAS CATO-C4X-119891)
- Eltrombopag Impurity 87 (CAS CATO-C4X-119887)
- Eltrombopag Impurity 88 (CAS CATO-C4X-119888)
- Eltrombopag Impurity 41 (CAS 303730-26-9)
- Eltrombopag Impurity 100 (CAS 15969-09-2)
Recommended Standards
- Z-Pyr-OtBu (CAS 81470-51-1)
- Hyoscine N-oxide (CAS 97-75-6)
- p-Hydroxycocaine (100 ?g/mL in Methanol) (CAS 89339-16-2)
- Bisacodyl Impurity 10 (CAS CATO-C4X-203710)
- Ruxolitinib Impurity 42 (CAS CATO-C4X-205842)
- Doxylamine Impurity 15 (CAS CATO-C4X-178915)
- Pitavastatin Impurity 36 (CAS CATO-C4X-103736)
- 2-((1H-Imidazol-2-yl)thio)-5-fluoroaniline (CAS 88251-70-1)
- 3-((9-Amino-7-ethoxyacridin-3-yl)diazenyl)pyridine-2,6-diamine (CAS 681282-09-7)
- Cinacalcet Impurity 61 (CAS CATO-C4X-105961)
- 5-Azaspiro[3.4]Octane-6,8-dione (CAS 1909305-14-1)
- 2-Chloro-5-[(3-methyl-1-piperidinyl)sulfonyl]-aniline (CAS 1036526-86-9)
- 3-Cyano-6-nitro-2-phenyl-2H-indazole 1-oxide (CAS 93716-53-1)
- Anti-TF Antigen Peptide P30-1 trifluoroacetate salt (CAS 573664-50-3)
Why CATO?
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