Eltrombopag Impurity 29 CAS CATO-C4X-119829
| CAS No. | CATO-C4X-119829 |
| Molecular Formula | C27H27N5O4 |
| Molecular Weight | 485.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Eltrombopag Impurity 29 (CAS CATO-C4X-119829) is a certified pharmaceutical impurity reference standard with the molecular formula C27H27N5O4 and a molecular weight of 485.53 g/mol.
The molecular framework of Eltrombopag Impurity 29 (C27H27N5O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Eltrombopag Impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H27N5O4 |
| Molecular Weight | 485.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Eltrombopag Standards
- Eltrombopag Impurity 27 (CAS CATO-C4X-119827)
- Eltrombopag Impurity 97 (CAS CATO-C4X-119897)
- Eltrombopag Impurity 23 (CAS CATO-C4X-119823)
- Eltrombopag Impurity 25 (CAS CATO-C4X-119825)
- Eltrombopag Impurity 80 (CAS CATO-C4X-119880)
- Eltrombopag impurity 148 (CAS CATO-C4X-1198148)
- Eltrombopag Impurity 12 (CAS 376592-56-2)
- Eltrombopag impurity 146 (CAS CATO-C4X-1198146)
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