Eltrombopag Impurity 47 CAS CATO-C4X-119847
| CAS No. | CATO-C4X-119847 |
| Molecular Formula | C26H18N2O7 |
| Molecular Weight | 470.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Eltrombopag Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Eltrombopag Impurity 47 (CAS CATO-C4X-119847, C26H18N2O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C26H18N2O7, Eltrombopag Impurity 47 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 470.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C26H18N2O7 |
| Molecular Weight | 470.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Eltrombopag Standards
- Eltrombopag Impurity 130 (CAS CATO-C4X-1198130)
- Eltrombopag Impurity 22 (CAS CATO-C4X-119822)
- Eltrombopag Ethyl Ester (CAS CATO-C4X-11983)
- Eltrombopag Impurity 132 (CAS CATO-C4X-1198132)
- Eltrombopag Impurity 5 (CAS CATO-C4X-11985)
- Eltrombopag Impurity 77 (CAS CATO-C4X-119877)
- Eltrombopag impurity 146 (CAS CATO-C4X-1198146)
- Eltrombopag Impurity 12 (CAS 376592-56-2)
Recommended Standards
- ((2S,3R,4R,5R,6R)-3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)-4-(((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)-L-serine (CAS 60280-57-1)
- Minocycline Impurity 59 (CAS CATO-C4X-169959)
- (2R)-2-{2-[(3R)-6-(4-Carbamimidamidobenzoyloxy)-2,3-dihydro-1-benzofuran-3-yl]acetamido}butanedioic acid (CAS 1802888-10-3)
- 4-Acetamidophenyl-d3-2,3,4-tri-O-acetyl-β-D-glucuronide, Methyl Ester (CAS 1260619-58-6)
- Levosimendan Impurity 36 (CAS CATO-C4X-130836)
- Vincamine EP Impurity B (CAS 6835-99-0)
- Amlodipine Impurity 119 (CAS CATO-C4X-1095119)
- 1,2,3,4-Tetrahydroacridine-9-carboxamide (CAS 42878-53-5)
- 4-(3-Oxobutyl)benzamide (CAS 74248-67-2)
- N-Ethyl-5-methylbenzo[d]isoxazol-3-amine (CAS 1344687-58-6)
- tert-Butyl (5-methyl-2-nitrophenyl)carbamate (CAS 1566792-15-1)
- 1-Cyclopentyl-1,4-diazepane bis(4-methylbenzenesulfonate) (CAS 1255718-36-5)
- 3-Hydroxy Anagrelide-13C3 (CAS 1219393-12-0)
- Tau Peptide (401-411)-Lys-Lys trifluoroacetate salt (CAS 2022956-59-6)
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