Eltrombopag Impurity 96 CAS CATO-C4X-119896
| CAS No. | CATO-C4X-119896 |
| Molecular Formula | C25H22N4O4 |
| Molecular Weight | 442.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Eltrombopag Impurity 96 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Eltrombopag Impurity 96 (CAS CATO-C4X-119896, C25H22N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Eltrombopag Impurity 96 (C25H22N4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 442.47 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Eltrombopag Impurity 96 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H22N4O4 |
| Molecular Weight | 442.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Eltrombopag Standards
Recommended Standards
- Cefuroxime Impurity 96 (CAS CATO-C4X-124596)
- Cefcapene Impurity 51 (CAS CATO-C4X-182451)
- Moxifloxacin impurity 132 (CAS CATO-C4X-1074132)
- Venetoclax Impurity 76 (CAS CATO-C4X-249576)
- Betamethasone Impurity 2 (CAS CATO-C4X-14372)
- Cefcapene Impurity 98 (CAS CATO-C4X-182498)
- AZD-9291 Impurity 14 (CAS 1975982-94-5)
- 3,6-Dihydro-4,6,6-trimethyl-2h-pyran-2-one (CAS 22954-83-2)
- N-Cyclohexyl-2-nitrobenzenesulfonamide (CAS 77516-53-1)
- (S)-2-Bromosuccinic Acid (CAS 20859-23-8)
- trans (4-Hydroxycyclohexyl)-pyrrolidin-1-yl-methanone (CAS 1932817-37-2)
- Ethyl 2-(4-chloro-3-methoxyphenyl)acetate (CAS 1056987-17-7)
- (R)-N,3-Dimethyl-N-(4-(4-methylpiperidin-1-yl)butan-2-yl)benzenesulfonamide (CAS 195199-95-2)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
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