Simvastatin Impurity 20 CAS CATO-C4X-119920

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-119920
Molecular FormulaC30H51NO5
Molecular Weight505.73 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Simvastatin Impurity 20 CAS CATO-C4X-119920 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 505.73 g/mol gives Simvastatin Impurity 20 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Simvastatin Impurity 20 (CAS CATO-C4X-119920), a pharmacopoeial impurity reference standard (molecular formula C30H51NO5, MW 505.73 g/mol) used for the identification and quantification of trace impurities in APIs.

Simvastatin Impurity 20 (C30H51NO5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC30H51NO5
Molecular Weight505.73 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms1

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