Cefotaxime Impurity 81 CAS CATO-C4X-120181
| CAS No. | CATO-C4X-120181 |
| Molecular Formula | C16H17N5O7S2 |
| Molecular Weight | 455.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cefotaxime Impurity 81 is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Cefotaxime Impurity 81 (CAS CATO-C4X-120181, C16H17N5O7S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H17N5O7S2, Cefotaxime Impurity 81 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 455.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Cefotaxime Impurity 81 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H17N5O7S2 |
| Molecular Weight | 455.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Cefotaxime Standards
- Cefotaxime Impurity 27 (CAS CATO-C4X-120127)
- Cefotaxime Impurity 28 (CAS CATO-C4X-120128)
- Cefotaxime EP Impurity D (CAS 63527-53-7)
- Cefotaxime (CAS 63527-52-6)
- Cefotaxime Impurity 65 (CAS CATO-C4X-120165)
- E-Cefotaxime S-Oxide (CAS 69132-42-9)
- Cefotaxime S-Oxide (CAS 97466-27-8)
- (E)-Cefotaxime S-Oxide (CAS CATO-C4X-120131)
Recommended Standards
- Etrasimod Impurity 59 (CAS CATO-C4X-321459)
- Fluocinolone Acetonide-13C3 (CAS 1262192-25-5)
- Cefixime Impurity 28 (CAS CATO-C4X-113928)
- Geranylgeranyl Diphosphate (GGPP) (CAS 104715-21-1)
- Aztreonam impurity 77 (CAS CATO-C4X-152277)
- Dexrazoxane Impurity 15 (CAS CATO-C4X-202015)
- CAS 31264-06-9 (CAS 31264-06-9)
- (R)-1-[4-(Trifluoromethyl)phenyl]ethylamine (CAS 578027-35-7)
- N-Boc-7-azaspiro[3.5]nonan-2-amine (CAS 147611-03-8)
- (2-Methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-8-yl)methanamine (CAS 1423033-42-4)
- 3-(Tert-butyl)-5-fluorobenzaldehyde (CAS 1123172-37-1)
- 3-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid (CAS 3734-24-5)
- 2-Methoxyphenyl benzoate (CAS 531-37-3)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com