Fluocinolone Acetonide-13C3 CAS 1262192-25-5
| CAS No. | 1262192-25-5 |
| Molecular Formula | C21[13C]3H30F2O6 |
| Molecular Weight | 455.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Fluocinolone Acetonide-13C3 (CAS 1262192-25-5), molecular formula C21[13C]3H30F2O6 and molecular weight 455.47 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Fluocinolone Acetonide-13C3 (C21[13C]3H30F2O6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21[13C]3H30F2O6 |
| Molecular Weight | 455.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide Impurity 31 (CAS 1178-54-7)
- Fluocinolone Acetonide Impurity 3 (CAS 4306-83-6)
- Fluocinolone Acetonide Impurity 40 (CAS CATO-C4X-238140)
- Fluocinolone Acetonide EP Impurity J (CAS 1361531-95-4)
- Fluocinolone Acetonide EP Impurity K (CAS CATO-C4X-238111)
- Fluocinolone Acetonide (CAS 67-73-2)
- Fluocinolone Acetonide Impurity 38 (CAS CATO-C4X-238138)
- Fluocinolone Acetonide Impurity 41 (CAS CATO-C4X-238141)
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Why CATO?
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