Cefotiam Impurity 18 CAS CATO-C4X-120418
| CAS No. | CATO-C4X-120418 |
| Molecular Formula | C18H25N9O5S3 |
| Molecular Weight | 543.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Cefotiam Impurity 18 (C18H25N9O5S3) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Cefotiam Impurity 18 (CAS CATO-C4X-120418), a pharmacopoeial impurity reference standard (molecular formula C18H25N9O5S3, MW 543.64 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Cefotiam Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H25N9O5S3 |
| Molecular Weight | 543.64 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 9 |
| Sulfur Atoms | 3 |
Related Cefotiam Standards
- Cefotiam Impurity 27 (CAS CATO-C4X-120427)
- Cefotiam Impurity 52 (CAS CATO-C4X-120452)
- Cefotiam Impurity 53 (CAS CATO-C4X-120453)
- Cefotiam Impurity 19 (CAS CATO-C4X-120419)
- Cefotiam Impurity 11 (CAS CATO-C4X-120411)
- Cefotiam Impurity 17 (CAS CATO-C4X-120417)
- Cefotiam Impurity 24 (CAS CATO-C4X-120424)
- delta(3)-Cefotiam (CAS 142182-63-6)
Recommended Standards
- (3-(1-((Tert-butoxycarbonyl)amino)-2-(1-tosyl-1H-indol-3-yl)ethyl)oxetan-3-yl)glycine (CAS 2199281-10-0)
- 1-[3-[2-[1-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-hydroxy-ethylidene]hydrazino]propyl]pyrrole-2,5-dione (CAS 1618096-56-2)
- Fmoc-Phe-Arg-OH (CAS 250695-64-8)
- 2-Chloro-9-[2-deoxy-2-fluoro-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-B-D-arabinofuranosyl]-9H-purin-6-amine (CAS 134646-41-6)
- Bepotastine Impurity 7 (CAS CATO-C4X-18397)
- Ibuprofen EP Impurity A (CAS CATO-C4X-1082147)
- Estradiol Valerate impurity 21 (CAS 1313382-32-9)
- [4-(4-Amino-2-chloro-phenyl)piperazin-1-yl]-(o-tolyl)methanone (CAS 640759-19-9)
- Benzyl 2-[Benzyl[2-(Boc-amino)ethyl]amino]acetate (CAS 174799-94-1)
- MX2 hydrochloride (CAS 131722-57-1)
- N-(3-methoxybenzyl)-2-methylcyclohexan-1-amine (CAS 418777-72-7)
- 3,4-Bis(4-methoxyphenyl)-5-methylisoxazole (CAS 78967-05-2)
- 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid (CAS 6266-66-6)
- Peptide Impurity 82 (CAS 10491-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com