Cefotiam Impurity 47 CAS CATO-C4X-120447
| CAS No. | CATO-C4X-120447 |
| Molecular Formula | C21H28N10O4S3 |
| Molecular Weight | 580.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cefotiam Impurity 47 is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Cefotiam Impurity 47 (CAS CATO-C4X-120447, C21H28N10O4S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefotiam Impurity 47 (C21H28N10O4S3) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H28N10O4S3 |
| Molecular Weight | 580.71 g/mol |
| Purity | ＞90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 10 |
| Sulfur Atoms | 3 |
Related Cefotiam Standards
- Cefotiam Impurity 33 (CAS CATO-C4X-120433)
- Cefotiam Impurity 18 (CAS CATO-C4X-120418)
- Cefotiam Impurity 27 (CAS CATO-C4X-120427)
- Cefotiam Impurity 52 (CAS CATO-C4X-120452)
- Cefotiam Impurity 53 (CAS CATO-C4X-120453)
- Cefotiam Impurity 19 (CAS CATO-C4X-120419)
- Cefotiam Impurity 11 (CAS CATO-C4X-120411)
- Cefotiam Impurity 17 (CAS CATO-C4X-120417)
Recommended Standards
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- 5,7-Dichloro-2,3-dihydro-1H-inden-1-amine (CAS 1188163-79-2)
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