N-Nitroso Cefpirome impurity 56 CAS CATO-C4X-120756
| CAS No. | CATO-C4X-120756 |
| Molecular Formula | C26H27N3O2P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-Nitroso Cefpirome impurity 56 (CAS CATO-C4X-120756), a pharmacopoeial impurity reference standard (molecular formula C26H27N3O2PBr, MW 524.40 g/mol) used for the identification and quantification of trace impurities in APIs.
N-Nitroso Cefpirome impurity 56 (C26H27N3O2PBr) contains a steroid core, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H27N3O2P Br |
| Molecular Weight | 524.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
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- Avanafil Impurity 119 (CAS CATO-C4X-1118119)
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- 1-(pyridazin-3-yl)-1,4-diazepane (CAS 223797-25-9)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
Why CATO?
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