Posaconazole Impurity 154 CAS CATO-C4X-1208154
| CAS No. | CATO-C4X-1208154 |
| Molecular Formula | C29H37N5O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Posaconazole Impurity 154 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Posaconazole Impurity 154 (CAS CATO-C4X-1208154), a pharmacopoeial impurity reference standard (molecular formula C29H37N5O3HCl, MW 540.11 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C29H37N5O3HCl, Posaconazole Impurity 154 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 540.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H37N5O3 HCl |
| Molecular Weight | 540.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Posaconazole Standards
- Posaconazole Impurity 25 (CAS 1042398-26-4)
- Posaconazole Impurity 112 (CAS 110931-77-6)
- Posaconazole Impurity 111 (CAS 112559-81-6)
- Posaconazole-d4 (CAS 1133712-26-1)
- Posaconazole Impurity 84 (CAS 122151-32-0)
- Posaconazole Impurity 115 (CAS 122151-38-6)
- Posaconazole Impurity 67(R,S,R,R) (CAS 1229428-89-0)
- Posaconazole Impurity 22(R,S,S,R) (CAS 1229428-90-3)
Recommended Standards
- Cefpirome Impurity 35 (CAS CATO-C4X-120735)
- Solifenacin EP Impurity A (CAS 118864-75-8)
- Clopidogrel EP impurity A (CAS 144457-28-3)
- Fmoc-D-Cys(Bzl)-OH (CAS 252049-18-6)
- 1-((2R,3S,4R,5R)-3-chloro-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 1673560-41-2)
- ethyl 5-hydroxypyrazine-2-carboxylate (CAS 54013-03-5)
- 4,4'-Bicyclohexanol (mixture of isomers) (CAS 20601-38-1)
- 2-(4-Bromo-6-iodopyridin-2-yl)acetic acid (CAS 1393574-50-9)
- 3-(Cyclopentyloxy)propane-1-sulfonyl chloride (CAS 1340581-53-4)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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