Posaconazole Impurity 253 CAS CATO-C4X-1208254
| CAS No. | CATO-C4X-1208254 |
| Molecular Formula | C23H21N3O5 |
| Molecular Weight | 419.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Posaconazole Impurity 253 (CAS CATO-C4X-1208254), a pharmacopoeial impurity reference standard (molecular formula C23H21N3O5, MW 419.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C23H21N3O5, Posaconazole Impurity 253 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 419.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H21N3O5 |
| Molecular Weight | 419.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Posaconazole Standards
- Posaconazole Impurity 32 (CAS CATO-C4X-120832)
- Posaconazole Impurity 122 (CAS 687132-01-0)
- Posaconazole Impurity N1 (CAS 2170933-06-7)
- Posaconazole impurity 225 (CAS CATO-C4X-1208225)
- Posaconazole impurity 228 (CAS CATO-C4X-1208228)
- Posaconazole Impurity 25 (CAS 1042398-26-4)
- Posaconazole Impurity 44 (CAS 357189-97-0)
- Posaconazole Impurity 257 (CAS CATO-C4X-1208257)
Recommended Standards
- Mirabegron Impurity 68 (CAS CATO-C4X-103268)
- Aztreonam impurity 120 (CAS CATO-C4X-1522120)
- Trimethyl 2,2',2''-nitrilotribenzoate (CAS 34069-90-4)
- Aminomethylbenzoic Acid Impurity 2 (CAS 98270-32-7)
- Cyanocobalamin /Vitamin B12 Impurity 36 (CAS CATO-C4X-187436)
- Formoterol impurity 38 (CAS CATO-C4X-1525138)
- Fluorometholone Impurity 7 (CAS 2796-99-8)
- 2-Bromo-6-fluoro-4-methoxybenzaldehyde (CAS 856767-10-7)
- Tert-butyl 2-(methylamino)butanoate (CAS 1248382-70-8)
- 5-Chloro-2-(3-methylpiperazin-1-yl)pyrimidine hydrochloride (CAS 1420846-53-2)
- 6-Amino-1-methyl-5-propylpyrimidine-2,4(1H,3H)-dione (CAS 98427-48-6)
- Posaconazole impurity 222 (CAS CATO-C4X-1208222)
- Adenosine Impurity 6 (CAS 321-30-2)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com