Posaconazole Impurity 64 CAS CATO-C4X-120864
| CAS No. | CATO-C4X-120864 |
| Molecular Formula | C40H46N8O5 |
| Molecular Weight | 718.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Posaconazole Impurity 64 (C40H46N8O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Posaconazole Impurity 64 (CAS CATO-C4X-120864, C40H46N8O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Posaconazole Impurity 64 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H46N8O5 |
| Molecular Weight | 718.84 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Posaconazole Standards
- Posaconazole Formylurea Analogue (CAS CATO-C4X-1208192)
- Posaconazole Impurity 37 (CAS CATO-C4X-120837)
- Posaconazole Impurity 155 (CAS CATO-C4X-1208155)
- Posaconazole impurity 233 (CAS CATO-C4X-1208233)
- Posaconazole Impurity 259 (CAS CATO-C4X-1208259)
- Posaconazole Impurity 48 (CAS 1902954-03-3)
- Posaconazole Impurity 49 (CAS 1902954-05-5)
- Posaconazole Impurity 51 (CAS 357189-94-7)
Recommended Standards
- A 54556A (CAS 95398-45-1)
- 5,10-Bis(4-(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl)-5,10-dihydrophenazine (CAS 1638702-85-8)
- Cucurbitacin E-2-O-glucoside (CAS 1398-78-3)
- Ibrutinib Impurity 119 (CAS CATO-C4X-1064119)
- Netupitant Impurity 36 (CAS CATO-C4X-122336)
- Avibactam Impurity 126 (CAS CATO-C4X-1348126)
- Voriconazole Impurity N1 (CAS 929249-84-3)
- 5-Cyclopropoxy-2-methoxybenzoic acid (CAS 1243355-70-5)
- (3-Amino-4-((4-chlorophenyl)sulfonyl)-5-(o-tolylamino)thiophen-2-yl)(p-tolyl)methanone (CAS 1115322-99-0)
- (S)-1-(3,5-difluorophenyl)-2-methoxyethan-1-amine (CAS 1269956-43-5)
- 3-Benzyl-1-(3-chloro-4-fluorophenyl)-1-(2-hydroxy-3-methoxybenzyl)thiourea (CAS 306730-50-7)
- cis-2,6-Dimethylpiperidin-4-one (CAS 13200-35-6)
- Ethyl 6-(tert-butyl)-3-cyano-2-hydroxyisonicotinate (CAS 100616-09-9)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
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