Voriconazole Impurity N1 CAS 929249-84-3
| CAS No. | 929249-84-3 |
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Voriconazole Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Voriconazole Impurity N1 (CAS 929249-84-3, C8H5ClF2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Voriconazole Impurity N1 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Voriconazole Standards
- Voriconazole Impurity 60 (CAS 116622-90-3)
- Voriconazole Impurity 59 (CAS 141060-00-6)
- Voriconazole Impurity 77 (CAS 137234-85-6)
- Voriconazole Impurity 71 (CAS 1359667-92-7)
- Voriconazole Impurity 65 (CAS 3741-24-0)
- Voriconazole Impurity 70 (CAS 115617-41-9)
- Voriconazole Impurity 44 (CAS 1289559-66-5)
- Voriconazole Impurity 65 (CAS 1289559-76-7)
Recommended Standards
- 2-Chloro-2,5-difluoroacetophenone (CAS 60468-36-2)
- 2,3 - Difluoro - 4 - methylbenzoyl chloride 2,3-Difluoro-4-methyl-benzoyl chloride 2,3-difluoro-p-toluoyl chloride 261763-38-6 benzoyl chloride, 2,3-difluoro-4-methyl- (CAS 261763-38-6)
- 2-Chloro-1-(3,5-difluorophenyl)ethan-1-one (CAS 920023-60-5)
- Fluconazole Impurity 11 (CAS 51336-94-8)
- Cyclophosphamide EP Impurity F (CAS 1071-28-9)
- Docetaxel Impurity 67 (CAS 124605-42-1)
- Cefazolin Impurity 69 (CAS CATO-C4X-157769)
- Tert-butyl 2-(methylamino)benzoate (CAS 121506-08-9)
- 1-(2,4-Dihydroxyphenyl)-2-(4-nitrophenyl)ethan-1-one (CAS 15485-63-9)
- 4-(3-Hydroxypropoxy)-2,3-dimethylpyridine 1-oxide (CAS 209914-28-3)
- (S)-2-Amino-2-(2-bromo-5-methoxyphenyl)ethan-1-ol (CAS 1213097-83-6)
- ((9H-Fluoren-2-yl)methyl)hydrazine (CAS 887593-05-7)
- 1,4-Bis((2-ethylhexyl)amino)-5,8-dihydroxyanthracene-9,10-dione (CAS 295800-70-3)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com