Ceftazidime Impurity 83 CAS CATO-C4X-121283
| CAS No. | CATO-C4X-121283 |
| Molecular Formula | C6H7N3O3S |
| Molecular Weight | 201.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ceftazidime Impurity 83 (CAS CATO-C4X-121283, C6H7N3O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ceftazidime Impurity 83 (C6H7N3O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 201.20 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7N3O3S |
| Molecular Weight | 201.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ceftazidime Standards
- Ceftazidime Impurity 28 (CAS 50382-11-1)
- Ceftazidime Impurity 48 (CAS 64513-00-4)
- Ceftazidime Impurity 88 (CAS CATO-C4X-121288)
- (Z)-Ceftazidime Impurity 36 (CAS CATO-C4X-121236)
- (E)-Ceftazidime Impurity 37 (CAS CATO-C4X-121237)
- Ceftazidime Impurity 22 (CAS 5408-04-8)
- Ceftazidime Impurity 111 (CAS CATO-C4X-1212111)
- Ceftazidime Impurity 18 (CAS CATO-C4X-121218)
Recommended Standards
- (E)-Cefotaxime Impurity 25 (CAS 66341-09-1)
- Levocarnitine Impurity N20 (CAS 41363-39-7)
- Cefepime EP Impurity D (CAS 65872-41-5)
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- Toceranib Impurity 4 (CAS CATO-C4X-25854)
- Ticagrelor Impurity 112 (CAS CATO-C4X-1093112)
- Goserelin BP Impurity 3 Acetate (CAS CATO-C4X-192033)
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- CyclopentylmethanamineHCl (CAS 58714-85-5)
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- (3,4-Dihydro-2H-benzo[b][1,4]oxazin-7-yl)methanol (CAS 1216033-20-3)
- 6-(4-Chlorophenyl)-3-(pyridin-4-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (CAS 85106-54-3)
- 3-(4-Mesityl-5-methylthiazol-2-yl)aniline (CAS 1416338-74-3)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
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