(E)-Ceftazidime Impurity 37 CAS CATO-C4X-121237
| CAS No. | CATO-C4X-121237 |
| Molecular Formula | C6H8BrNO4 |
| Molecular Weight | 238.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies (E)-Ceftazidime Impurity 37 (CAS CATO-C4X-121237), a pharmacopoeial impurity reference standard (molecular formula C6H8BrNO4, MW 238.04 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, (E)-Ceftazidime Impurity 37 (C6H8BrNO4) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 238.04 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8BrNO4 |
| Molecular Weight | 238.04 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (Z)-Ceftazidime Impurity 36 (CAS CATO-C4X-121236)
- Ceftazidime Impurity 88 (CAS CATO-C4X-121288)
- Ceftazidime Impurity 111 (CAS CATO-C4X-1212111)
- Ceftazidime Impurity 18 (CAS CATO-C4X-121218)
- Ceftazidime Impurity 48 (CAS 64513-00-4)
- Ceftazidime Impurity 26 (CAS CATO-C4X-121226)
- Ceftazidime Impurity 38 Mixture (CAS 91999-75-6)
- Ceftazidime Impurity 83 (CAS CATO-C4X-121283)
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