Ceftazidime Impurity 89 CAS CATO-C4X-121289

Purity ≥90%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-121289
Molecular FormulaC12H8N4O2S3
Molecular Weight336.41 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ceftazidime Impurity 89 CAS CATO-C4X-121289 chemical structure

Description

Ceftazidime Impurity 89 (CAS CATO-C4X-121289) is a certified pharmaceutical impurity reference standard with the molecular formula C12H8N4O2S3 and a molecular weight of 336.41 g/mol.

The molecular framework of Ceftazidime Impurity 89 (C12H8N4O2S3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Ceftazidime Impurity 89 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H8N4O2S3
Molecular Weight336.41 g/mol
Purity≥90%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms4
Sulfur Atoms3

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