Ceftazidime Impurity 47 CAS 199923-06-3
| CAS No. | 199923-06-3 |
| Molecular Formula | C14H21N3O5S |
| Molecular Weight | 343.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ceftazidime Impurity 47 (CAS 199923-06-3, C14H21N3O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Ceftazidime Impurity 47 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 343.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ceftazidime Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H21N3O5S |
| Molecular Weight | 343.40 g/mol |
| Purity | ≥90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ceftazidime Standards
- Ceftazidime Impurity 27 (CAS 83654-89-1)
- Ceftazidime Impurity 89 (CAS CATO-C4X-121289)
- Ceftazidime Impurity 16 (CAS 86299-47-0)
- Ceftazidime Impurity 46 (CAS 134203-50-2)
- Ceftazidime Impurity 50 (CAS 1924627-99-5)
- Ceftazidime Impurity 58 (CAS CATO-C4X-121258)
- Ceftazidime Impurity 85 (CAS CATO-C4X-121285)
- Ceftazidime Impurity 57 (CAS CATO-C4X-121257)
Recommended Standards
- Alvimopan impurity 17 (CAS CATO-C4X-114517)
- Faropenem Impurity 76 (CAS CATO-C4X-128976)
- tert-Butyl (S)-4-((benzyloxy)methyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide (CAS 2250039-78-0)
- Diltiazem EP Impurity B (CAS 87447-47-0)
- chondroitin sulfate impurity A (CAS CATO-C4X-32811)
- Methocarbamol Impurity 6 (CAS 28066-53-7)
- Famotidine EP Impurity B Dimaleate (CAS 109467-08-5)
- N-(2-Hydroxyethyl) 2-bromo-5-fluorobenzamide (CAS 951884-16-5)
- Dorzagliatin Impurity 20 (CAS CATO-C4X-344120)
- 4-(Difluoromethyl)-3,5-dimethoxypicolinonitrile (CAS 1806039-84-8)
- Benzyl 3-(4-methoxyphenyl)pyrrolidine-1-carboxylate (CAS 1210754-14-5)
- ASP9521 (CAS 1126084-37-4)
- Apixaban Impurity 28 (CAS 503612-76-8)
- Semaglutide Impurity 123 (CAS 71997-93-8)
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