Netupitant Impurity 52 CAS CATO-C4X-122352
| CAS No. | CATO-C4X-122352 |
| Molecular Formula | C26H21ClN4O2 |
| Molecular Weight | 456.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Netupitant Impurity 52 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 456.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Netupitant Impurity 52 (CAS CATO-C4X-122352), a pharmacopoeial impurity reference standard (molecular formula C26H21ClN4O2, MW 456.92 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Netupitant Impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H21ClN4O2 |
| Molecular Weight | 456.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Netupitant Standards
- Netupitant Impurity 62 (CAS CATO-C4X-122362)
- Netupitant Impurity 43 (CAS CATO-C4X-122343)
- Netupitant Impurity 38 (CAS CATO-C4X-122338)
- Netupitant Impurity 45 (CAS 1648578-86-2)
- Netupitant Impurity 22 (CAS CATO-C4X-122322)
- Netupitant Impurity 50 (CAS CATO-C4X-122350)
- Netupitant Impurity 12 (CAS CATO-C4X-122312)
- Netupitant Impurity 8 (CAS CATO-C4X-12238)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com