Atovaquone Impurity 6 CAS CATO-C4X-15516

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-15516
Molecular FormulaC10H6O3
Molecular Weight174.15 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Atovaquone Impurity 6 CAS CATO-C4X-15516 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 174.15 g/mol gives Atovaquone Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Atovaquone Impurity 6 (CAS CATO-C4X-15516), a pharmacopoeial impurity reference standard (molecular formula C10H6O3, MW 174.15 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Atovaquone Impurity 6 (C10H6O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Atovaquone Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H6O3
Molecular Weight174.15 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present

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