Doxepin Impurity 1 CAS CATO-C4X-12261

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-12261
Molecular FormulaC19H21NO2
Molecular Weight295.38 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Doxepin Impurity 1 CAS CATO-C4X-12261 chemical structure

Description

As a process- or degradation-related impurity, Doxepin Impurity 1 (CAS CATO-C4X-12261, C19H21NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Doxepin Impurity 1 (C19H21NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Doxepin Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC19H21NO2
Molecular Weight295.38 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms1

Related Doxepin Standards

Recommended Standards

Why CATO?