Candesartan Cilexetil Impurity 27 CAS CATO-C4X-123427
| CAS No. | CATO-C4X-123427 |
| Molecular Formula | C10H8N2O5 |
| Molecular Weight | 236.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Candesartan Cilexetil Impurity 27 (CAS CATO-C4X-123427, C10H8N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Candesartan Cilexetil Impurity 27 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Candesartan Cilexetil Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O5 |
| Molecular Weight | 236.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Candesartan Standards
- Candesartan Cilexetil Impurity 29 (CAS 16533-45-2)
- Candesartan Cilexetil Impurity 30 (CAS 90322-71-7)
- Candesartan Cilexetil Impurity 36 (CAS CATO-C4X-123436)
- Candesartan Cilexetil Impurity 47 (CAS CATO-C4X-123447)
- Candesartan Impurity 6 (CAS 142269-40-7)
- Candesartan Cilexetil Impurity 25 (CAS 99464-83-2)
- Candesartan Impurity N1 (CAS 1246817-06-0)
- Candesartan Cilexetil Impurity 32 (CAS 62351-79-5)
Recommended Standards
- (6-Nitro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid 694499-69-9 8267AE C10H8N2O5 (CAS 694499-69-9)
- Enarodustat Impurity 27 (CAS CATO-C4X-322827)
- (E)-4-(3-nitrophenylamino)-4-oxobut-2-enoic acid 36847-90-2 4-(3-Nitroanilino)-4-oxobut-2-enoic acid (CAS 36847-90-2)
- Acrolein 2,4-Dinitrophenylhydrazone (CAS 888-54-0)
- Tucatinib Impurity 15 (CAS CATO-C4X-260515)
- Sofosbuvir Impurity 47 (CAS CATO-C4X-105247)
- Lumefantrine Impurity N1 (CAS 2170653-95-7 (free base))
- (2-Amino-2-oxoethyl)glycine (CAS 7365-83-5)
- Bicyclo[3.1.0]hexan-2-amine (CAS 1258639-94-9)
- 4-(4-Phenylmethoxyphenoxy)aniline (CAS 155828-47-0)
- Benzyl(S)-(1-(4-hydroxyphenyl)-2-(pyrrolidin-1-yl)propan-2-yl)(methyl)carbamatehydrochloride (CAS 2007908-62-3)
- 8-(phenylmethyl)-2,8-Diazaspiro[4.5]decane-1,3-dione (CAS 1463-48-5)
- Difelikefalin Impurity 50 (CAS CATO-C4X-304150)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
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