Tucatinib Impurity 15 CAS CATO-C4X-260515
| CAS No. | CATO-C4X-260515 |
| Molecular Formula | C27H22N8O3 |
| Molecular Weight | 506.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Tucatinib Impurity 15 (CAS CATO-C4X-260515, C27H22N8O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Tucatinib Impurity 15 (C27H22N8O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Tucatinib Impurity 15 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H22N8O3 |
| Molecular Weight | 506.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Tucatinib Standards
- Tucatinib Impurity 62 (E-Isomer) (CAS CATO-C4X-260562)
- Tucatinib Impurity 4 (CAS 1429755-58-7)
- Tucatinib Impurity 1 (CAS CATO-C4X-26051)
- Tucatinib Impurity 16 (CAS CATO-C4X-260516)
- Tucatinib Impurity 2 (CAS CATO-C4X-26052)
- Tucatinib Impurity 3 (CAS CATO-C4X-26053)
- Tucatinib Impurity 4 (CAS CATO-C4X-26054)
- Tucatinib Impurity 5 (CAS CATO-C4X-26055)
Recommended Standards
- Silodosin impurity 24 (CAS CATO-C4X-175424)
- (6-(1,10-Phenanthrolin-3-yl)naphthalen-2-yl)diphenylphosphine oxide (CAS 1480371-38-7)
- Silodosin Impurity 20 (CAS CATO-C4X-175420)
- Vardenafil Impurity N1 (CAS 448184-56-3)
- Etoricoxib Impurity 2 (CAS 316149-01-6)
- Mirogabalin Impurity 138 (CAS CATO-C4X-2924138)
- Cefazolin Impurity 73 (CAS CATO-C4X-157773)
- 2-(Pyridin-3-yl)ethan-1-amine dihydrochloride (CAS 90345-16-7)
- (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4,4-difluoropiperidine-2-carboxylic acid (CAS 1221793-52-7)
- 1-(4-Bromophenyl)-2-(ethylsulfonyl)-3-hydroxypropan-1-one (CAS 1707402-92-3)
- 2-(5-(Pyridin-3-yl)isoxazol-3-yl)ethan-1-amine (CAS 1352512-40-3)
- tert-butyl 5-azaspiro[3.4]oct-7-ene-5-carboxylate (CAS 1955548-11-4)
- (5S)-5-{[(3-pyridinylmethyl)amino]methyl}-2-pyrrolidinone dihydrochloride (CAS 1609388-34-2)
- Des-Leu26-Tirzepatide (CAS CATO-CPTD788947)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com