Isavuconazole Impurity 105 CAS CATO-C4X-1236105
| CAS No. | CATO-C4X-1236105 |
| Molecular Formula | C12H11F2N3O |
| Molecular Weight | 251.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Isavuconazole Impurity 105 (CAS CATO-C4X-1236105, C12H11F2N3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Isavuconazole Impurity 105 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 251.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11F2N3O |
| Molecular Weight | 251.23 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Isavuconazole Standards
- Isavuconazole Impurity 103 (CAS CATO-C4X-1236103)
- Isavuconazole Impurity 104 (CAS 2922040-42-2)
- Isavuconazole Impurity 129 (CAS 2122222-15-3)
- Isavuconazole impurity 71 (CAS CATO-C4X-1236171)
- Isavuconazole Impurity 195 (CAS CATO-C4X-1236195)
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole Impurity 43 (CAS CATO-C4X-123643)
- Isavuconazole Impurity 222 (CAS CATO-C4X-1236222)
Recommended Standards
- Moxifloxacin Impurity 61 (CAS CATO-C4X-107461)
- 2-bromanyl-3-hexyl-thiophene 2-bromo-3-hexylthiophene 69249-61-2 A836409 (CAS 69249-61-2)
- 210705-84-3 2-Bromo-4-hexylthiophene DTXSID80448244 (CAS 210705-84-3)
- Efinaconazole Impurity 14 (CAS 135270-10-9)
- Mirogabalin Impurity 163 (CAS CATO-C4X-2924163)
- Linagliptin impurity 99 (CAS CATO-C4X-110199)
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- 4-Bromo-2-ethynylphenol (CAS 2228319-60-4)
- 3-(1H-pyrazol-1-yl)-1,2,3,4-tetrahydroquinoline (CAS 1251322-20-9)
- L-Alanine-2-d1-N-t-BOC (CAS 88181-11-7)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
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