Isavuconazole Impurity 226 CAS CATO-C4X-1236226
| CAS No. | CATO-C4X-1236226 |
| Molecular Formula | C12H10F2N4S |
| Molecular Weight | 280.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, Isavuconazole Impurity 226 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Isavuconazole Impurity 226 (CAS CATO-C4X-1236226), a pharmacopoeial impurity reference standard (molecular formula C12H10F2N4S, MW 280.30 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10F2N4S |
| Molecular Weight | 280.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 223 (CAS CATO-C4X-1236223)
- Isavuconazole Impurity 229 (CAS CATO-C4X-1236229)
- Isavuconazole Impurity 7 (CAS 2733698-17-2)
- Isavuconazole Impurity 79 (CAS 483340-20-1)
- Isavuconazole Impurity 1 (CAS 2069200-13-9)
- Isavuconazole Impurity 108 (CAS CATO-C4X-1236108)
- Isavuconazole Impurity 158 (CAS CATO-C4X-1236158)
- Isavuconazole Impurity 2 (CAS 2001051-99-4)
Recommended Standards
- 83905-96-8 11-Methylundecanoatephosphonic acid MFCD17012687 (CAS 83905-96-8)
- Aztreonam impurity 71 (CAS CATO-C4X-152271)
- N-Hydroxy-5-((p-tolylsulfinyl)methyl)isoxazole-3-carboxamide (CAS 823220-30-0)
- Albendazole impurity 31 (CAS CATO-C4X-153531)
- Relebactam Impurity 75 (CAS CATO-C4X-214475)
- Duloxetine EP Impurity E (CAS 1033803-59-6)
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- 2-((Hex-5-en-1-yloxy)methyl)tetrahydro-2H-pyran (CAS 52426-80-9)
- Tetradecanenitrile (CAS 629-63-0)
- tert-Butyl 6-bromo-3-formyl-1H-indazole-1-carboxylate (CAS 1365803-32-2)
- 2-(Acetoxymethoxy)-1,3-propanediyl-d5 Dibenzoate (CAS 1185159-39-0)
- [(4-chlorophenyl)methyl][2-(3,4-diethoxyphenyl)ethyl]amine (CAS 1011399-13-5)
- 3-(Dimethylamino)-2,2-dimethyl-1-(4-(methylsulfonyl)phenyl)propan-1-one hydrochloride (CAS 54076-97-0)
- Renin Inhibitor Peptide (CAS 50410-01-0)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com