Isavuconazole Impurity 52 CAS CATO-C4X-123652
| CAS No. | CATO-C4X-123652 |
| Molecular Formula | C13H16Cl2N2O5 |
| Molecular Weight | 351.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Isavuconazole Impurity 52 (CAS CATO-C4X-123652, C13H16Cl2N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C13H16Cl2N2O5, Isavuconazole Impurity 52 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 351.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H16Cl2N2O5 |
| Molecular Weight | 351.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Isavuconazole Standards
- Isavuconazole Impurity 196 (CAS CATO-C4X-1236196)
- Isavuconazole Impurity 197 (CAS CATO-C4X-1236197)
- Isavuconazole Impurity 102 (CAS 1884463-51-7)
- Isavuconazole impurity 65 (CAS CATO-C4X-1236165)
- Isavuconazole impurity 67 (CAS CATO-C4X-1236167)
- Isavuconazole Impurity 218 (CAS CATO-C4X-1236218)
- Isavuconazole Impurity 219 (CAS CATO-C4X-1236219)
- Isavuconazole Impurity 159 (CAS CATO-C4X-1236159)
Recommended Standards
- Prop-2-yn-1-yl N-{1-[(2,6-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}carbamate (CAS 400084-78-8)
- 7-Bromo-2-(naphthalen-1-yl)-4H-chromen-4-one (CAS 1063978-38-0)
- Prop-2-yn-1-yl (1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate (CAS 338755-62-7)
- (5-Bromo-2-methoxyphenyl)(3,5-dimethoxyphenyl)methanone (CAS 1094749-23-1)
- Bendamustine Impurity 38 (CAS CATO-C4X-127138)
- Pemafibrate Impurity 97 (CAS CATO-C4X-290397)
- Paliperidone impurity 146 (CAS CATO-C4X-1724146)
- 2-(1-Aminopropan-2-yl)-6-hydroxypyrimidin-4(3h)-one (CAS 1343685-64-2)
- Ethyl 2-(2,3-dichlorophenyl)-2-(methylamino)acetate (CAS 1217998-26-9)
- N-((4-bromothiophen-2-yl)methyl)-1-methylcyclohexan-1-amine (CAS 1247458-41-8)
- 4-(tert-Butoxy)-2-(methylamino)phenol (CAS 1243394-64-0)
- 4-Cyano-2,5-difluorobenzoic acid (CAS 198280-48-7)
- 2-(2-Methyl-3-(trifluoromethyl)phenyl)acetonitrile (CAS 1000515-00-3)
- Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) (H-7266.1000) (CAS 922704-18-5)
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