Isavuconazole impurity 67 CAS CATO-C4X-1236167
| CAS No. | CATO-C4X-1236167 |
| Molecular Formula | C17H21F2N3O3 |
| Molecular Weight | 353.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 353.36 g/mol gives Isavuconazole impurity 67 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Isavuconazole impurity 67 (CAS CATO-C4X-1236167) is a certified pharmaceutical impurity reference standard with the molecular formula C17H21F2N3O3 and a molecular weight of 353.36 g/mol.
The molecular framework of Isavuconazole impurity 67 (C17H21F2N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H21F2N3O3 |
| Molecular Weight | 353.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Isavuconazole Standards
- Isavuconazole Impurity 102 (CAS 1884463-51-7)
- Isavuconazole impurity 65 (CAS CATO-C4X-1236165)
- Isavuconazole Impurity 52 (CAS CATO-C4X-123652)
- Isavuconazole Impurity 196 (CAS CATO-C4X-1236196)
- Isavuconazole Impurity 197 (CAS CATO-C4X-1236197)
- Isavuconazole Impurity 219 (CAS CATO-C4X-1236219)
- Isavuconazole Impurity 218 (CAS CATO-C4X-1236218)
- Isavuconazole Impurity 67 (CAS CATO-C4X-123667)
Recommended Standards
- Efinaconazole Impurity 2 (CAS 135133-23-2)
- ethyl 4-(3-(1,3-dioxoisoindolin-2-yl)propoxy)benzoate (CAS 100840-55-9)
- Lansoprazole EP Impurity C/USP Impurity B (CAS 103577-40-8)
- Methyl 1-(2-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011397-81-1)
- Furosemide Impurity 27 (CAS 2760-11-4)
- Prochlorperazine Impurity 6 (CAS CATO-C4X-19666)
- Etrasimod Impurity 77 (CAS CATO-C4X-321477)
- (Z)-2-(2,5-dimethoxybenzylidene)quinuclidin-3-one (CAS 315244-82-7)
- Ethyl 3,4-diaminopicolinate (CAS 1823962-72-6)
- 1-tert-Butyl-1h-imidazole-5-carbaldehyde (CAS 1314981-20-8)
- Annonacin-10-One (CAS 123266-21-7)
- 1-(1h-1,3-Benzodiazol-2-yl)-3-methylbutan-1-amine dihydrochloride (CAS 25810-67-7)
- Bromocyclododecane (CAS 7795-35-9)
- D-Ile17-Tirzepatide (CAS CATO-CPTD788917)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com