N-Nitroso Gatifloxacin Impurity 24 CAS CATO-C4X-125324
| CAS No. | CATO-C4X-125324 |
| Molecular Formula | C19H20BF3N4O5 |
| Molecular Weight | 452.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
N-Nitroso Gatifloxacin Impurity 24 (C19H20BF3N4O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, N-Nitroso Gatifloxacin Impurity 24 (CAS CATO-C4X-125324, C19H20BF3N4O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H20BF3N4O5 |
| Molecular Weight | 452.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- N-Nitroso Lorlatinib impurity 1 (CAS CATO-C4X-30911)
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- N-Nitroso Oxacillin Impurity 63 (CAS CATO-C4X-232163)
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- N-Nitroso Flucloxacillin Impurity 21 (CAS CATO-C4X-164721)
Recommended Standards
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- 5,8-Bis(5-bromo-2-thienyl)quinoxaline (CAS 1007128-59-7)
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- 2-([1,1'-Biphenyl]-4-yl)-5-(trifluoromethyl)-1,3,4-oxadiazole (CAS 887267-97-2)
- Ethyl 3-(2-nitrophenyl)acrylate (CAS 2437-05-0)
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