Buspirone EP Impurity H HCl CAS CATO-C4X-12588
| CAS No. | CATO-C4X-12588 |
| Molecular Formula | C33H50N8O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Buspirone EP Impurity H HCl (CAS CATO-C4X-12588) is a certified pharmaceutical impurity reference standard with the molecular formula C33H50N8O4HCl and a molecular weight of 659.27 g/mol.
The molecular framework of Buspirone EP Impurity H HCl (C33H50N8O4HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Buspirone EP Impurity H HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C33H50N8O4 2*HCl |
| Molecular Weight | 659.27 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Buspirone Standards
- Buspirone impurity 01 (CAS 105496-33-1)
- Buspirone EP Impurity K (CAS 1075-89-4)
- Buspirone EP Impurity A-d8 (Buspirone USP Related Compound A-d8) (CAS 1309283-31-5)
- Buspirone Impurity 9 (CAS 13220-24-1)
- Buspirone Impurity 21 (CAS 137583-05-2)
- Buspirone Impurity 24 (CAS 1800242-04-9)
- Buspirone Impurity 20 (CAS 1821194-01-7)
- Buspirone Impurity 23 (CAS 20261-27-2)
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