Cefalexin Impurity 46 CAS CATO-C4X-126146
| CAS No. | CATO-C4X-126146 |
| Molecular Formula | C16H18N4O6S |
| Molecular Weight | 394.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cefalexin Impurity 46 is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Cefalexin Impurity 46 (CAS CATO-C4X-126146, C16H18N4O6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefalexin Impurity 46 (C16H18N4O6S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18N4O6S |
| Molecular Weight | 394.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Cefalexin Standards
- Cefalexin Impurity 50 (CAS CATO-C4X-126150)
- Cefalexin Impurity 49 (CAS CATO-C4X-126149)
- Cefalexin Monohydrate EP Impurity F (CAS CATO-C4X-122442)
- Cefalexin EP Impurity F (CAS 79750-46-2)
- Cefalexin (CAS 15686-71-2)
- Cefalexin Impurity 30 (CAS 65870-51-1)
- Cefalexin Impurity 45 (CAS CATO-C4X-126145)
- Cefalexin Impurity 43 (CAS CATO-C4X-126143)
Recommended Standards
- N-Nitroso Amoxicillin Impurity 98 (CAS CATO-C4X-114898)
- Bumetanide Impurity 10 (CAS CATO-C4X-198610)
- N-Nitroso Amoxicillin EP Impurity C (CAS CATO-C4X-114876)
- Z-Phe-Ala-diazomethylketone (CAS 71732-53-1)
- Clozapine impurity 9 (CAS 27696-24-8)
- Norethisterone EP Impurity A (CAS 31528-46-8)
- Promethazine Impurity 52 (CAS CATO-C4X-141852)
- N-(thiazol-2-ylmethyl)thiophene-2-carboxamide (CAS 1329038-92-7)
- 4-Isothiocyanatooxane (CAS 1153383-87-9)
- 2-[1-(4-fluorophenyl)-1H-pyrazol-4-yl]-1-methyl-5-oxopyrrolidine-3-carbonitrile (CAS 1803598-23-3)
- H-Phe-Gly-NH2 . HCl (G-2885.0001) (CAS 38678-61-4)
- 1142215-88-0 9472AC C20H24N2O6 [{2-[(2,3-Dimethoxybenzyl)amino]-2-oxoethyl}-(4-methoxyphenyl)amino]acetic acid (CAS 1142215-88-0)
- 1-(2-Propyloxazolidin-3-yl)ethanone (CAS 138531-19-8)
- Peptide Impurity 12 (CAS CATO-CPTD788812)
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