Bendamustine Impurity 10 CAS CATO-C4X-127110
| CAS No. | CATO-C4X-127110 |
| Molecular Formula | C20H29Cl2N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bendamustine Impurity 10 (CAS CATO-C4X-127110) is a certified pharmaceutical impurity reference standard with the molecular formula C20H29Cl2N3O2HCl and a molecular weight of 450.83 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Bendamustine Impurity 10 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 450.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bendamustine Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H29Cl2N3O2 HCl |
| Molecular Weight | 450.83 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Bendamustine Standards
- Bendamustine impurity 33 (CAS 109882-25-9)
- Bendamustine Impurity 2 (CAS 109882-26-0)
- Bendamustine USP Related Compound E (CAS 109882-27-1)
- Bendamustine Dihydroxy Impurity (CAS 109882-29-3)
- Bendamustine USP Related Compound A (CAS 109882-30-6)
- Bendamustine-D8 Hydrochloride (CAS 1134803-33-0)
- Bendamustine Impurity 7 (CAS 1138238-08-0)
- Bendamustine Dideschloroethyl Acid Hydrochloride (CAS 1179363-38-2)
Recommended Standards
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- (R)-2-(Pyrrolidin-3-yl)propan-2-ol hydrochloride (CAS 2203403-97-6)
- 2-Ethoxy-5-fluoro-4-methoxyaniline (CAS 1342034-65-4)
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- N-phenyl-3,4-dihydroquinoline-1(2H)-carboxamide (CAS 349454-54-2)
- 2-cyano-1-ethylguanidine (CAS 24010-80-8)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
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