Bendamustine Impurity 14 CAS CATO-C4X-127114
| CAS No. | CATO-C4X-127114 |
| Molecular Formula | C19H27Cl2N3O3 |
| Molecular Weight | 416.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Bendamustine Impurity 14 (CAS CATO-C4X-127114, C19H27Cl2N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Bendamustine Impurity 14 (C19H27Cl2N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Bendamustine Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H27Cl2N3O3 |
| Molecular Weight | 416.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Bendamustine Standards
- Bendamustine Impurity 15 (CAS CATO-C4X-127115)
- Bendamustine USP Related Compound I (CAS 87475-54-5)
- Bendamustine impurity 32 (CAS CATO-C4X-127132)
- Bendamustine impurity 43 (CAS CATO-C4X-127143)
- Bendamustine Isopropyl Ester (CAS 1313020-25-5)
- Bendamustine Impurity 19 (CAS CATO-C4X-127119)
- Bendamustine Impurity 20 (CAS CATO-C4X-127120)
- Bendamustine Impurity 26 (CAS 2489521-68-6)
Recommended Standards
- N,2-bis(3-(trifluoromethyl)phenyl)thiazole-4-carboxamide (CAS 303998-61-0)
- Iofendylate (CAS 99-79-6)
- Sodium Cromoglicate Impurity 5 (CAS CATO-C4X-20115)
- 2-Phenyl-4-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide (CAS 400080-76-4)
- Phenylephrine Impurity 80 (CAS CATO-C4X-146780)
- Apalutamide Impurity 49 (CAS CATO-C4X-274949)
- Tofacitinib Impurity 39 (CAS 2459302-80-6)
- 6-(Pyrimidin-4-yloxy)-2-azaspiro[3.3]heptane (CAS 1774895-94-1)
- Methyl 5-(hydroxymethyl)-2-methyl-1H-pyrrole-3-carboxylate (CAS 2089213-09-0)
- Sodium 2-(dimethylamino)-1-hydroxyethanesulfonate (CAS 1433960-19-0)
- 2-((6-Aminonaphthalen-2-yl)sulfonyl)ethan-1-ol (CAS 52218-35-6)
- (4S,5S)-1,3-Bis(2,6-dimethylphenyl)-4,5-diphenyl-4,5-dihydro-1H-imidazol-3-ium tetrafluoroborate (CAS 1033618-43-7)
- 4-Chloro-2-(piperidin-1-yl)benzaldehyde, 97% (CAS 1027803-23-1)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com