Tacrolimus Impurity 3 CAS CATO-C4X-13003
| CAS No. | CATO-C4X-13003 |
| Molecular Formula | C44H67NO11 |
| Molecular Weight | 786.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Tacrolimus Impurity 3 (C44H67NO11) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 786.00 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Tacrolimus Impurity 3 (CAS CATO-C4X-13003, C44H67NO11) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tacrolimus Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C44H67NO11 |
| Molecular Weight | 786.00 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus EP Impurity I (CAS 104987-16-8)
- Tacrolimus Impurity 54 (CAS CATO-C4X-130054)
- Tacrolimus Impurity 58 (CAS CATO-C4X-130058)
- Tacrolimus Impurity 52 (CAS CATO-C4X-130052)
- Tacrolimus Impurity 32 (CAS 129039-81-2)
- Tacrolimus 31 DMT (CAS 135635-47-1)
- Tacrolimus 15-DMT (CAS 151039-41-7)
- Tacrolimus 31-DMT (CAS 127984-76-3)
Recommended Standards
- CAS 129212-37-9 (CAS 129212-37-9)
- Allisartan Isoproxil Impurity 19 (CAS CATO-C4X-321719)
- Leucomycin Hydrate (CAS 1392-21-8)
- Josamycin EP Impurity H (KitasaMycin A1) (CAS 16846-34-7)
- Ranitidine Impurity 17 (CAS CATO-C4X-137017)
- Bromhexine Impurity N2 (CAS 63471-27-2)
- Talazoparib Impurity 4 (CAS 1322879-81-1)
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- N-Ethyl-N-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)ethanamine (CAS 2377606-38-5)
- Glucagon Monohydrochloride (CAS 28270-04-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com