Penehyclidine Impurity 8 CAS CATO-C4X-13048
| CAS No. | CATO-C4X-13048 |
| Molecular Formula | C21H31ClNO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Penehyclidine Impurity 8 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Penehyclidine Impurity 8 (CAS CATO-C4X-13048) is a certified pharmaceutical impurity reference standard with the molecular formula C21H31ClNO2Cl and a molecular weight of 400.38 g/mol.
Penehyclidine Impurity 8 (C21H31ClNO2Cl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H31ClNO2 Cl |
| Molecular Weight | 400.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Penehyclidine Standards
- Penehyclidine Impurity 9 ((R,R)-Penehyclidine) (CAS 114121-68-5)
- Penehyclidine impurity 12 (CAS 151673-91-5)
- Penehyclidine Impurity 1 (CAS 151673-92-6)
- Penehyclidine HCl (CAS 151937-76-7)
- Penehyclidine Impurity 9 (CAS 183201-49-2)
- Penehyclidine Impurity 3 (CAS 2091937-84-5)
- Penehyclidine Impurity 3 HCI (CAS 2091937-84-5（free base）)
- Penehyclidine Impurity 25 Hydrochloride (CAS 2091937-85-6)
Recommended Standards
- Cefotiam Impurity 33 (CAS CATO-C4X-120433)
- Betamethasone Impurity N22 (CAS 116522-68-0)
- Dydrogesterone Impurity 7 (CAS 19592-55-3)
- 2-Propenoic acid, 2-methyl-, polymer with butyl 2-propenoate, methyl 2-methyl-2-propenoate and 2-propenoic acid (CAS 27791-81-7)
- [2-(5,7-Dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)ethyl]amine hydrochloride (CAS 1986791-73-4)
- Bacitracin A (CAS 22601-59-8)
- 5-Bromo-2-cyclopropylthiophene-3-carboxylic acid (CAS 2594436-03-8)
- Methyl 2-methylpyrrolidine-3-carboxylate hydrochloride (CAS 1803567-37-4)
- (2-Fluoro-3-nitrophenyl)methanol (CAS 946126-95-0)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com