Levosimendan Impurity 43 CAS CATO-C4X-130843
| CAS No. | CATO-C4X-130843 |
| Molecular Formula | C18H22N4O5 |
| Molecular Weight | 374.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Levosimendan Impurity 43 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Levosimendan Impurity 43 (CAS CATO-C4X-130843, C18H22N4O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H22N4O5, Levosimendan Impurity 43 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 374.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H22N4O5 |
| Molecular Weight | 374.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Levosimendan Standards
- Levosimendan Impurity 64 (CAS CATO-C4X-130864)
- Levosimendan Impurity 66 (CAS CATO-C4X-130866)
- Levosimendan Impurity 57 (CAS CATO-C4X-130857)
- Levosimendan Impurity 65 (CAS CATO-C4X-130865)
- Levosimendan Impurity 10 (CAS CATO-C4X-130810)
- Levosimendan Impurity 17 (CAS CATO-C4X-130817)
- Levosimendan Impurity 47 (CAS CATO-C4X-130847)
- Levosimendan Impurity 84 (CAS CATO-C4X-130884)
Recommended Standards
- Vonoprazan Impurity 303 (CAS CATO-C4X-1020303)
- Lercanidipine Impurity 1 (CAS 225785-54-6)
- Vonoprazan Impurity 176 (CAS 2932441-73-9)
- Nimodipine Impurity 37 (CAS 39562-18-0)
- Atrasentan Impurity 45 (CAS 1059044-82-4)
- Avanafil Impurity 6 (CAS 330784-50-4)
- Rivastigmine Impurity 15 (CAS 71607-31-3(free base))
- 6-(Azetidin-3-ylmethoxy)quinoline hydrochloride (CAS 1823796-16-2)
- 2-Bromo-5-methoxy-3H-imidazo[4,5-b]pyridine (CAS 2092849-43-7)
- Nystatin A1 (CAS 34786-70-4)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-fluoro-5-iodopyridine (CAS 1807133-49-8)
- N-(4-Methylbenzyl)-1,2,3-thiadiazole-4-carboxamide (CAS 606102-01-6)
- 1142204-76-9 9317AC C19H22N2O5 [{2-[(3,4-Dimethoxybenzyl)amino]-2-oxoethyl}(phenyl)amino]acetic acid (CAS 1142204-76-9)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
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