Avanafil Impurity 6 CAS 330784-50-4
| CAS No. | 330784-50-4 |
| Molecular Formula | C23H27N7O3 |
| Molecular Weight | 449.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Avanafil Impurity 6 (CAS 330784-50-4, C23H27N7O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Avanafil Impurity 6 (C23H27N7O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H27N7O3 |
| Molecular Weight | 449.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 7 |
Related Avanafil Standards
- Avanafil Impurity 148 (CAS CATO-C4X-1118148)
- Avanafil Impurity 130 (CAS CATO-C4X-1118130)
- Avanafil Impurity 104 (CAS CATO-C4X-1118104)
- Avanafil Impurity 3 (CAS 1364671-52-2)
- Avanafil Impurity 155 (CAS CATO-C4X-1118155)
- Avanafil Impurity 63 (CAS CATO-C4X-111863)
- Avanafil Impurity 21 (CAS CATO-C4X-111821)
- Avanafil Impurity 139 (CAS CATO-C4X-1118139)
Recommended Standards
- Parecoxib Impurity 74 (CAS CATO-C4X-159174)
- Pitavastatin Impurity 6 (CAS 172336-33-3)
- (S)-2-(2'-(Diphenylphosphanyl)-[1,1'-biphenyl]-2-yl)-4-isopropyl-4,5-dihydrooxazole (CAS 904887-75-8)
- Pitavastatin Impurity 110 (CAS CATO-C4X-1037110)
- Buspirone Impurity N1 (CAS 5662-95-3)
- Tirofiban Impurity 100 (CAS CATO-C4X-1254100)
- Ozenoxacin Impurity 52 (CAS CATO-C4X-279652)
- tert-Butyl (8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)carbamate (CAS 1950635-34-3)
- Benzyl N-[(1R,3S)-3-aminocyclopentyl]carbamate oxalate (CAS 1418119-71-7)
- 1,3-Dimethyl-2-methyleneimidazolidine (CAS 68738-47-6)
- 1-(3-Chlorophenyl)-4-(3-(trifluoromethyl)phenyl)-1H-pyrazole (CAS 318288-92-5)
- 4-Amino-3-(1-methyl-1h-imidazol-5-yl)butanoic acid (CAS 1514656-32-6)
- 1-Benzyl-1H-pyrazolo[3,4-d]pyridazin-4(5H)-one (CAS 41075-01-8)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com