Pregabalin Impurity 143 CAS CATO-C4X-1312143

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1312143
Molecular FormulaC10H21NO2
Molecular Weight187.28 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Pregabalin Impurity 143 CAS CATO-C4X-1312143 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Pregabalin Impurity 143 (CAS CATO-C4X-1312143) is a certified pharmaceutical impurity reference standard with the molecular formula C10H21NO2 and a molecular weight of 187.28 g/mol.

Pregabalin Impurity 143 (C10H21NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H21NO2
Molecular Weight187.28 g/mol
Purity≥95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
Nitrogen Atoms1

Related Pregabalin Standards

Recommended Standards

Why CATO?