Pregabalin Impurity 136 CAS CATO-C4X-1312136
| CAS No. | CATO-C4X-1312136 |
| Molecular Formula | C9H17NO3 |
| Molecular Weight | 187.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pregabalin Impurity 136 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Pregabalin Impurity 136 (CAS CATO-C4X-1312136, C9H17NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Pregabalin Impurity 136 (C9H17NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H17NO3 |
| Molecular Weight | 187.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| Nitrogen Atoms | 1 |
Related Pregabalin Standards
- Pregabalin Impurity 19 (CAS CATO-C4X-131219)
- Pregabalin Impurity 23 (CAS 181289-34-9)
- Pregabalin Impurity 60 (CAS 181289-33-8)
- Pregabalin Impurity 76 (CAS 181289-15-6)
- Pregabalin impurity 96 (CAS CATO-C4X-131296)
- Pregabalin Impurity 143 (CAS CATO-C4X-1312143)
- Pregabalin Impurity 68 (CAS 1568110-05-3)
- Pregabalin Impurity 2 (CAS 75143-89-4)
Recommended Standards
- Levocarnitine Impurity 40 (CAS CATO-C4X-129240)
- Sitagliptin Impurity 80 (CAS 220199-85-9)
- Levetiracetam Impurity 20 (CAS 1867585-44-1)
- Tert-Butyl Cyclobutoxycarbamate (CAS CATO-C3D-262617)
- Metoprolol Impurity 48 (CAS CATO-C4X-136748)
- Safinamide Impurity 56 (CAS CATO-C4X-159056)
- Orforglipron impurity 64 (CAS CATO-C4X-323464)
- N-((R)-1-((S)-2-Amino-3-methylbutanoyl)pyrrolidin-3-yl)-N-methylacetamide (CAS 1401665-69-7)
- 2-(2,3-Dihydro-1h-inden-1-yl)propanoic acid (CAS 55288-73-8)
- Echinatine N-oxide (CAS 20267-93-0)
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- 4,5,6,7-Tetrahydrobenzo[d]isoxazol-3-ol (CAS 27772-90-3)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
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