N-Nitroso Nafamostat impurity 116 CAS CATO-C4X-1332116
| CAS No. | CATO-C4X-1332116 |
| Molecular Formula | C19H14N8O5 |
| Molecular Weight | 434.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-Nitroso Nafamostat impurity 116 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, N-Nitroso Nafamostat impurity 116 (CAS CATO-C4X-1332116, C19H14N8O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
N-Nitroso Nafamostat impurity 116 (C19H14N8O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures N-Nitroso Nafamostat impurity 116 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14N8O5 |
| Molecular Weight | 434.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related N Standards
- N-Nitroso Nebivolol（and enantiomer） (CAS CATO-C4X-196838)
- N-Nitroso-Nebivolol (CAS CATO-CP114662)
- N-Nitroso Moxifloxacin D4 (CAS CATO-C4X-1074189)
- N-Nitroso Lisinopril (CAS 519175-80-5)
- N-Nitroso Ozanimod (CAS CATO-C4X-29023)
- N-Nitroso Lincomycin (CAS CATO-C4X-134240)
- N-Nitroso Terbutaline impurity 132 (CAS CATO-C4X-1183132)
- N-Nitroso Desmethyl Diltiazem-D3 (CAS CATO-C4X-136830)
Recommended Standards
- tert-Butyl (3-((3-bromobenzyl)oxy)-3-phenylpropyl)(methyl)carbamate (CAS 2593289-72-4)
- 3-((4-(Tert-butyl)benzyl)oxy)-N-(2,3-dichlorophenyl)thiophene-2-carboxamide (CAS 344270-78-6)
- 1-(4-((2-(Diallylamino)ethyl)amino)-6-methylpyrimidin-2-yl)-3-(3,4-dichlorophenyl)guanidine (CAS 51386-80-2)
- 3-((4-(Tert-butyl)benzyl)oxy)-N-(3,4-dichlorophenyl)thiophene-2-carboxamide (CAS 344270-52-6)
- Apremilast Impurity 87 (CAS 202262-76-8)
- Alverine Impurity 8 HCl (CAS 28031-50-7(free base))
- Fluticasone Furoate EP Impurity I (CAS 3086156-07-9)
- Sodium 4-isopropylbenzenesulfinate (CAS 89520-64-9)
- Pyrido[2,3-d]pyrimidine-4-carboxylic acid (CAS 2168847-74-1)
- (E)-3-(1h-Pyrrol-2-yl)acrylaldehyde (CAS 49616-64-0)
- 4,5,6,7-Tetrahydro-1h-indol-4-ol (CAS 192130-35-1)
- 1H-Benzo[d]azepin-2(3H)-one (CAS 19301-09-8)
- N-(3,4-Dihydro-2H-1-benzopyran-4-yl)-2-fluoropyridine-4-carboxamide (CAS 1304937-19-6)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com