Apremilast Impurity 87 CAS 202262-76-8
| CAS No. | 202262-76-8 |
| Molecular Formula | C8H7NO5 |
| Molecular Weight | 197.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Apremilast Impurity 87 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Apremilast Impurity 87 (CAS 202262-76-8), a pharmacopoeial impurity reference standard (molecular formula C8H7NO5, MW 197.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Apremilast Impurity 87 (C8H7NO5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H7NO5 |
| Molecular Weight | 197.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Nitrogen Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity N7 (CAS 2651-55-0)
- Apremilast Impurity 112 (CAS 247569-89-7)
- Apremilast Impurity 34 (CAS CATO-C4X-100934)
- Apremilast Impurity 47 (CAS 1956-36-1)
- Apremilast impurity 96 (CAS 856806-92-3)
- Apremilast impurity 97 (CAS 1000342-08-4)
- Apremilast Impurity 86 (CAS 106860-70-2)
- Apremilast Impurity 109 (CAS 2029-94-9)
Recommended Standards
- Methyl (4-nitrophenyl) carbonate (CAS 17175-16-5)
- Mesalazine Impurity 24 (CAS 859964-08-2)
- 4,7-Difluoro-1H-indole-2-carboxylic Acid (CAS 247564-67-6)
- Pomalidomide Impurity 62 (CAS CATO-C4X-135462)
- Vericiguat Impurity 79 (CAS CATO-C4X-289679)
- Salbutamol Impurity 117 (CAS CATO-C4X-1176117)
- Naproxen Impurity 54 (CAS 1268842-11-0)
- 7-Chloro-3-methoxyquinolin-4-ol (CAS 855871-35-1)
- 2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS 761440-11-3)
- 2-[(2-Bromophenyl)sulfanyl]cyclohexan-1-one (CAS 870297-90-8)
- Arnidiol (CAS 6750-30-7)
- 3-Bromo-1-isopropylpyridin-2(1h)-one (CAS 1780774-80-2)
- (7-Amino-4-methyl-1H-indol-2-yl)methanol (CAS 1352901-13-3)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com