Nafamostat Impurity 46 CAS CATO-C4X-133246
| CAS No. | CATO-C4X-133246 |
| Molecular Formula | C20H18N4O3 |
| Molecular Weight | 362.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Nafamostat Impurity 46 (CAS CATO-C4X-133246) is a certified pharmaceutical impurity reference standard with the molecular formula C20H18N4O3 and a molecular weight of 362.38 g/mol.
Based on its molecular formula C20H18N4O3, Nafamostat Impurity 46 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 362.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H18N4O3 |
| Molecular Weight | 362.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Nafamostat Standards
- Nafamostat Impurity 42 (CAS CATO-C4X-133242)
- Nafamostat impurity 98 (CAS CATO-C4X-133298)
- Nafamostat impurity 100 (CAS CATO-C4X-1332100)
- Nafamostat impurity 99 (CAS CATO-C4X-133299)
- Nafamostat impurity 101 (CAS CATO-C4X-1332101)
- Nafamostat-d4 (CAS CATO-C4X-133251)
- Nafamostat Impurity 3 (CAS CATO-C4X-13323)
- Nafamostat impurity 88 (CAS 2810790-31-7)
Recommended Standards
- Terbutaline impurity 138 (CAS CATO-C4X-1183138)
- Rebamipide Impurity 60 (CAS 135252-30-1)
- Edaravone Impurity 58 (CAS CATO-C4X-106258)
- Dexrazoxane Impurity 47 (CAS CATO-C4X-202047)
- Glycerol Impurity 15 (CAS CATO-C4X-217115)
- Ipratropium Impurity 25 (CAS CATO-C4X-166525)
- Mirogabalin Impurity 145 (CAS CATO-C4X-2924145)
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