Nafamostat impurity 99 CAS CATO-C4X-133299
| CAS No. | CATO-C4X-133299 |
| Molecular Formula | C22H17N3O3 |
| Molecular Weight | 371.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Nafamostat impurity 99 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 371.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Nafamostat impurity 99 (CAS CATO-C4X-133299), a pharmacopoeial impurity reference standard (molecular formula C22H17N3O3, MW 371.39 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H17N3O3 |
| Molecular Weight | 371.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Nafamostat Standards
- Nafamostat impurity 101 (CAS CATO-C4X-1332101)
- Nafamostat impurity 98 (CAS CATO-C4X-133298)
- Nafamostat Impurity 42 (CAS CATO-C4X-133242)
- Nafamostat Impurity 46 (CAS CATO-C4X-133246)
- Nafamostat impurity 75 (CAS 2623-40-7)
- Nafamostat Impurity 45 (CAS CATO-C4X-133245)
- Nafamostat impurity 107 (CAS CATO-C4X-1332107)
- Nafamostat impurity 100 (CAS CATO-C4X-1332100)
Recommended Standards
- Ceftriaxone EP Impurity E (CAS 58909-56-1)
- Isradipine (CAS 75695-93-1)
- Ceftriaxone Impurity 46 (CAS CATO-C4X-116346)
- Pyr-Trp-Gly-NH? (CAS 239134-47-5)
- Ramelteon Dimer Impurity (CAS 1365920-38-2)
- Limaprost Impurity 18 (CAS CATO-C4X-214518)
- Linezolid Impurity 16 (CAS CATO-C4X-107316)
- Heptane derivatives 1-17 (CAS CATO-C4X-226517)
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- Ethyl 3-amino-4-cyano-5-methyl-1H-pyrrole-2-carboxylate (CAS 74455-30-4)
- Ethyl 1-thia-4-azaspiro[4.4]Nonane-3-carboxylate hydrochloride (CAS 1236272-33-5)
- 116425-36-6 Curcumadione (CAS 116425-36-6)
- 4-Chloro-N-(thiophen-3-ylmethyl)benzenesulfonamide (CAS 1060229-77-7)
- (D-Tyr1,N-Me-Phe3)-Neuropeptide FF (H-4752.0001) (CAS 145274-93-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com