Sunitinib Impurity 23 CAS CATO-C4X-133323
| CAS No. | CATO-C4X-133323 |
| Molecular Formula | C18H17ClFN3O2 |
| Molecular Weight | 361.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Sunitinib Impurity 23 (CAS CATO-C4X-133323) is a certified pharmaceutical impurity reference standard with the molecular formula C18H17ClFN3O2 and a molecular weight of 361.80 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Sunitinib Impurity 23 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 361.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17ClFN3O2 |
| Molecular Weight | 361.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Sunitinib Standards
- Sunitinib Impurity 7 (CAS CATO-C4X-13337)
- Sunitinib Impurity 25 (CAS CATO-C4X-133325)
- Sunitinib Impurity 80 (CAS CATO-C4X-133380)
- Sunitinib Impurity 18 (CAS 326914-17-4)
- Sunitinib Impurity 19 (CAS 356068-97-8)
- Sunitinib Impurity 6 (CAS CATO-C4X-13336)
- Sunitinib Impurity 21 (CAS CATO-C4X-133321)
- Sunitinib Impurity 20 (CAS 873077-70-4)
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