Sunitinib Impurity 18 CAS 326914-17-4
| CAS No. | 326914-17-4 |
| Molecular Formula | C20H23FN4O2 |
| Molecular Weight | 370.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sunitinib Impurity 18 (CAS 326914-17-4), a pharmacopoeial impurity reference standard (molecular formula C20H23FN4O2, MW 370.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H23FN4O2, Sunitinib Impurity 18 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 370.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sunitinib Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23FN4O2 |
| Molecular Weight | 370.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Sunitinib Standards
- Sunitinib Impurity 19 (CAS 356068-97-8)
- Sunitinib Impurity 7 (CAS CATO-C4X-13337)
- Sunitinib Impurity 23 (CAS CATO-C4X-133323)
- Sunitinib Impurity 6 (CAS CATO-C4X-13336)
- Sunitinib Impurity 40 (CAS CATO-C4X-133340)
- Sunitinib Impurity 25 (CAS CATO-C4X-133325)
- Sunitinib Impurity 80 (CAS CATO-C4X-133380)
- Sunitinib Impurity 21 (CAS CATO-C4X-133321)
Recommended Standards
- Esomeprazole-d3 Sodium Salt (CAS CATO-C4X-111293)
- Amisulpride impurity 53 (CAS CATO-C4X-104553)
- Pioglitazone Ketone (M-III) (CAS 146062-45-5)
- Capecitabine-d11 (CAS 1132662-08-8)
- Landiolol Impurity 43 (CAS CATO-C4X-262143)
- Vonoprazan Impurity 105 (CAS CATO-C4X-1020105)
- Terazosin EP Impurity C HCl (CAS 60548-08-5)
- 1-(6-Nitro-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (CAS 174648-97-6)
- 2,5-Dimethyl-4-nitrobenzenesulfonamide (CAS 1698448-04-2)
- 4-Amino-1-methyl-2-(methylthio)-1H-imidazole-5-carbonitrile (CAS 586965-24-4)
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-5-methoxy-4-phenoxypyrimidine (CAS 339276-11-8)
- (1R,3S,5R)-4-((Z)-7-(Dimethylamino)hept-2-en-1-yl)-5-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentane-1,3-diol (CAS 67508-09-2)
- Palbociclib N-Glucuronide (CAS CATO-C4X-112535)
- Hexapeptide-9 (CAS 885024-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com